Modulation of Endothelial Inward-Rectifier K+ Current by Optical Isomers of Cholesterol
نویسندگان
چکیده
منابع مشابه
Modulation of endothelial inward-rectifier K+ current by optical isomers of cholesterol.
Membrane potential of aortic endothelial cells under resting conditions is dominated by inward-rectifier K(+) channels belonging to the Kir 2 family. Regulation of endothelial Kir by membrane cholesterol was studied in bovine aortic endothelial cells by altering the sterol composition of the cell membrane. Our results show that enriching the cells with cholesterol decreases the Kir current dens...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2002
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(02)75323-x